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TRIO

Welcome

This website provides information on patients with mutations in the TRIO gene, including clinical data, molecular data, management and research options.

The syndrome caused by mutations in the TRIO gene (formal designation “Mental retardation, autosomal dominant 44” – MIM #617061) is a multisystem disorder characterized by microcephaly, variable degrees of global developmental delay and/or intellectual disability, behavioural problems as well as minor hand abnormalities. Not all individuals with a mutation in the TRIO gene have these features.

This website was created to share and collect information about clinic, management and research projects to gather more knowledge and provide better treatment of patients with mutations in the TRIO gene.

Konstantinos Varvagiannis, MD Department of Genetics, Institute of Child Health, Athens, Greece knsvarv@ath.forthnet.gr

Lisenka E.L.M. Vissers, PhD Department of Human Genetics Radboud University Medical Center Nijmegen, The Netherlands Lisenka.Vissers@radboudumc.nl

Diana Baralle, BSc MBBS MD FRCP University of Southampton, Southampton General Hospital, Southampton, UK d.baralle@soton.ac.uk

Bert B.A. de Vries MD, PhD Department of Human Genetics Radboud University Medical Center Nijmegen, The Netherlands Bert.deVries@radboudumc.nl

To share and collect information about clinic management and research projects.

Clinical characteristics

Clinical characteristics

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Upload clinical information (professionals)

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Upload clinical information (parents)

Upload clinical information (parents)

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