Gender |
|
|
Male |
53.3% |
145/272 |
Female |
46.7% |
127/272 |
Indifferent |
0% |
0/272 |
Unknown |
0% |
0/272 |
General |
|
|
Motor delay |
97.8% |
224/229 |
Motor delay |
1.7% |
4/229 |
Abnormal renal morphology |
0.4% |
1/229 |
Bilateral cryptorchidism |
0.4% |
1/229 |
Hydronephrosis |
0.4% |
1/229 |
Speech delay |
97.6% |
246/252 |
Delayed speech and language development |
1.6% |
4/252 |
Intellectual disabillity |
97.6% |
244/250 |
Intellectual disability |
2.0% |
5/250 |
Abnormal renal morphology |
0.4% |
1/250 |
Bilateral cryptorchidism |
0.4% |
1/250 |
Hydronephrosis |
0.4% |
1/250 |
Neurology |
|
|
Neurological abnormalities |
85.6% |
208/243 |
Muscular hypotonia |
32.1% |
78/243 |
Generalized hypotonia |
17.3% |
42/243 |
Seizures |
15.6% |
38/243 |
Generalized tonic-clonic seizures |
7.8% |
19/243 |
Impaired pain sensation |
7.4% |
18/243 |
Neonatal hypotonia |
7.4% |
18/243 |
Febrile seizures |
4.5% |
11/243 |
Absence seizures |
4.1% |
10/243 |
Developmental regression |
3.7% |
9/243 |
EEG abnormality |
3.7% |
9/243 |
Astereognosia |
3.3% |
8/243 |
Central hypotonia |
3.3% |
8/243 |
Impaired visuospatial constructive cognition |
3.3% |
8/243 |
Visual agnosia |
3.3% |
8/243 |
Focal seizures with impairment of consciousness or awareness |
2.9% |
7/243 |
Gait ataxia |
2.5% |
6/243 |
Abnormality of the nervous system |
2.1% |
5/243 |
Abnormality of pain sensation |
2.1% |
5/243 |
Generalized tonic seizures |
2.1% |
5/243 |
Hypertonia |
1.6% |
4/243 |
Motor delay |
1.6% |
4/243 |
Atonic seizures |
1.2% |
3/243 |
Hyperreflexia |
1.2% |
3/243 |
Abnormality of nervous system physiology |
0.8% |
2/243 |
Broad-based gait |
0.8% |
2/243 |
Colpocephaly |
0.8% |
2/243 |
Delayed myelination |
0.8% |
2/243 |
Focal seizures without impairment of consciousness or awareness |
0.8% |
2/243 |
Focal seizures |
0.8% |
2/243 |
Gait disturbance |
0.8% |
2/243 |
Generalized seizures |
0.8% |
2/243 |
Generalized myoclonic seizures |
0.8% |
2/243 |
Headache |
0.8% |
2/243 |
Lower limb hyperreflexia |
0.8% |
2/243 |
Lower limb hypertonia |
0.8% |
2/243 |
Muscular hypotonia of the trunk |
0.8% |
2/243 |
Poor fine motor coordination |
0.8% |
2/243 |
Unsteady gait |
0.8% |
2/243 |
Upper limb hypertonia |
0.8% |
2/243 |
Abnormality of the subarachnoid space |
0.4% |
1/243 |
Abnormality of the corpus callosum |
0.4% |
1/243 |
Agenesis of corpus callosum |
0.4% |
1/243 |
Anomia |
0.4% |
1/243 |
Ataxia |
0.4% |
1/243 |
Cerebral palsy |
0.4% |
1/243 |
Dysarthria |
0.4% |
1/243 |
Dysdiadochokinesis |
0.4% |
1/243 |
Dyskinesia |
0.4% |
1/243 |
Dysmetria |
0.4% |
1/243 |
Dysplastic corpus callosum |
0.4% |
1/243 |
Dystonia |
0.4% |
1/243 |
Exercise intolerance |
0.4% |
1/243 |
Gait imbalance |
0.4% |
1/243 |
Gait apraxia |
0.4% |
1/243 |
Global developmental delay |
0.4% |
1/243 |
Hand tremor |
0.4% |
1/243 |
Infantile axial hypotonia |
0.4% |
1/243 |
Infantile muscular hypotonia |
0.4% |
1/243 |
Intellectual disability, borderline |
0.4% |
1/243 |
Muscle weakness |
0.4% |
1/243 |
Myoclonus |
0.4% |
1/243 |
Oromandibular dystonia |
0.4% |
1/243 |
Partial agenesis of the corpus callosum |
0.4% |
1/243 |
Poor gross motor coordination |
0.4% |
1/243 |
Posterior fossa cyst |
0.4% |
1/243 |
Postural instability |
0.4% |
1/243 |
Sensory impairment |
0.4% |
1/243 |
Torticollis |
0.4% |
1/243 |
Widened subarachnoid space |
0.4% |
1/243 |
Behavioral problems |
71.1% |
155/218 |
Autistic behavior |
30.3% |
66/218 |
Hyperactivity |
20.6% |
45/218 |
Attention deficit hyperactivity disorder |
14.7% |
32/218 |
Short attention span |
12.4% |
27/218 |
Autism |
11.5% |
25/218 |
Impaired social interactions |
7.8% |
17/218 |
Abnormal fear/anxiety-related behavior |
6.9% |
15/218 |
Aggressive behavior |
6.9% |
15/218 |
Stereotypic behavior |
6.9% |
15/218 |
Obsessive-compulsive behavior |
6.0% |
13/218 |
Abnormal social behavior |
5.0% |
11/218 |
Impulsivity |
5.0% |
11/218 |
Hyperkinesis |
4.6% |
10/218 |
Anxiety |
4.1% |
9/218 |
Behavioral abnormality |
3.2% |
7/218 |
Impaired social reciprocity |
2.8% |
6/218 |
Obsessive-compulsive trait |
2.8% |
6/218 |
Abnormal aggressive, impulsive or violent behavior |
1.8% |
4/218 |
Self-injurious behavior |
1.8% |
4/218 |
Abnormal emotion/affect behavior |
1.4% |
3/218 |
Drooling |
1.4% |
3/218 |
Absent speech |
0.9% |
2/218 |
Emotional lability |
0.9% |
2/218 |
Hyperacusis |
0.9% |
2/218 |
Inflexible adherence to routines or rituals |
0.9% |
2/218 |
Oral aversion |
0.9% |
2/218 |
Poor eye contact |
0.9% |
2/218 |
Sleep disturbance |
0.9% |
2/218 |
Abnormality of nervous system physiology |
0.5% |
1/218 |
Agoraphobia |
0.5% |
1/218 |
Clumsiness |
0.5% |
1/218 |
Developmental regression |
0.5% |
1/218 |
Facial tics |
0.5% |
1/218 |
Hair-pulling |
0.5% |
1/218 |
Happy demeanor |
0.5% |
1/218 |
Head-banging |
0.5% |
1/218 |
Impaired ability to form peer relationships |
0.5% |
1/218 |
Impaired pain sensation |
0.5% |
1/218 |
Lack of insight |
0.5% |
1/218 |
Nail-biting |
0.5% |
1/218 |
Overfriendliness |
0.5% |
1/218 |
Personality disorder |
0.5% |
1/218 |
Phonophobia |
0.5% |
1/218 |
Repetitive compulsive behavior |
0.5% |
1/218 |
Restlessness |
0.5% |
1/218 |
Restrictive behavior |
0.5% |
1/218 |
Rigidity |
0.5% |
1/218 |
Self-mutilation |
0.5% |
1/218 |
Shyness |
0.5% |
1/218 |
Violent behavior |
0.5% |
1/218 |
Brain abnormality |
71.1% |
143/201 |
Agenesis of corpus callosum |
19.4% |
39/201 |
Partial agenesis of the corpus callosum |
10.4% |
21/201 |
Hypoplasia of the corpus callosum |
8.0% |
16/201 |
Delayed myelination |
6.5% |
13/201 |
Colpocephaly |
5.5% |
11/201 |
Aplasia/Hypoplasia of the corpus callosum |
5.0% |
10/201 |
Enlarged cisterna magna |
5.0% |
10/201 |
Short corpus callosum |
3.5% |
7/201 |
Thick corpus callosum |
3.5% |
7/201 |
Abnormality of the corpus callosum |
3.0% |
6/201 |
Cerebellar cyst |
3.0% |
6/201 |
Dysplastic corpus callosum |
3.0% |
6/201 |
Retrocerebellar cyst |
3.0% |
6/201 |
Ventriculomegaly |
3.0% |
6/201 |
Arachnoid cyst |
2.5% |
5/201 |
Intracranial cystic lesion |
2.5% |
5/201 |
Arnold-Chiari type I malformation |
2.0% |
4/201 |
Cerebellar hypoplasia |
1.5% |
3/201 |
Cortical dysplasia |
1.5% |
3/201 |
Heterotopia |
1.5% |
3/201 |
Abnormal basal ganglia MRI signal intensity |
1.0% |
2/201 |
Abnormality of forebrain morphology |
1.0% |
2/201 |
Abnormality of lateral ventricle |
1.0% |
2/201 |
Absent septum pellucidum |
1.0% |
2/201 |
Aplasia/Hypoplasia of the cerebrum |
1.0% |
2/201 |
Attention deficit hyperactivity disorder |
1.0% |
2/201 |
Cerebral atrophy |
1.0% |
2/201 |
Cerebral hypoplasia |
1.0% |
2/201 |
Choroid plexus cyst |
1.0% |
2/201 |
Hydrocephalus |
1.0% |
2/201 |
Lambdoidal craniosynostosis |
1.0% |
2/201 |
Perivascular spaces |
1.0% |
2/201 |
Sagittal craniosynostosis |
1.0% |
2/201 |
Abnormality of the cerebellum |
0.5% |
1/201 |
Abnormal thalamic MRI signal intensity |
0.5% |
1/201 |
Abnormality of the cerebral ventricles |
0.5% |
1/201 |
Abnormality of corpus cavernosum |
0.5% |
1/201 |
Abnormality of neuronal migration |
0.5% |
1/201 |
Abnormality of cerebral veins |
0.5% |
1/201 |
Abnormality of the optic nerve |
0.5% |
1/201 |
Abnormality of midbrain morphology |
0.5% |
1/201 |
Abnormality of the periventricular white matter |
0.5% |
1/201 |
Abnormality of the pons |
0.5% |
1/201 |
Abnormal brainstem MRI signal intensity |
0.5% |
1/201 |
Abnormality of the cerebral white matter |
0.5% |
1/201 |
Abnormality of the choroid |
0.5% |
1/201 |
Abnormality of the cerebral cortex |
0.5% |
1/201 |
Abnormal cortical gyration |
0.5% |
1/201 |
Abnormal length of corpus callosum |
0.5% |
1/201 |
Aplasia/Hypoplasia involving the central nervous system |
0.5% |
1/201 |
Asymmetric ventricles |
0.5% |
1/201 |
Bilateral intracranial calcifications |
0.5% |
1/201 |
Brain atrophy |
0.5% |
1/201 |
Cavum septum pellucidum |
0.5% |
1/201 |
Cerebellar agenesis |
0.5% |
1/201 |
Cerebellar dysplasia |
0.5% |
1/201 |
Dandy-Walker malformation |
0.5% |
1/201 |
Delayed CNS myelination |
0.5% |
1/201 |
Dilation of lateral ventricles |
0.5% |
1/201 |
Encephalopathy |
0.5% |
1/201 |
Enlarged fetal cisterna magna |
0.5% |
1/201 |
Hypodysplasia of the corpus callosum |
0.5% |
1/201 |
Hypoplasia of the brainstem |
0.5% |
1/201 |
Hypoplastic olfactory lobes |
0.5% |
1/201 |
Hypoplasia of the pons |
0.5% |
1/201 |
Limbic malformations |
0.5% |
1/201 |
Microcephaly |
0.5% |
1/201 |
Midline central nervous system lipomas |
0.5% |
1/201 |
Multiple suture craniosynostosis |
0.5% |
1/201 |
Neonatal hypotonia |
0.5% |
1/201 |
Neoplasm of the central nervous system |
0.5% |
1/201 |
Pachygyria |
0.5% |
1/201 |
Polymicrogyria |
0.5% |
1/201 |
Prominent supraorbital ridges |
0.5% |
1/201 |
Relative macrocephaly |
0.5% |
1/201 |
Seizures |
0.5% |
1/201 |
Subarachnoid hemorrhage |
0.5% |
1/201 |
Syringomyelia |
0.5% |
1/201 |
Talipes calcaneovarus |
0.5% |
1/201 |
Facial abnormalities |
|
|
Abnormality of the ear |
61.3% |
146/238 |
Low-set ears |
13.9% |
33/238 |
Abnormality of the pinna |
8.8% |
21/238 |
Low-set, posteriorly rotated ears |
8.4% |
20/238 |
Abnormality of the ear |
5.9% |
14/238 |
Protruding ear |
5.5% |
13/238 |
Posteriorly rotated ears |
5.0% |
12/238 |
Macrotia |
4.2% |
10/238 |
Abnormality of the outer ear |
3.8% |
9/238 |
Uplifted earlobe |
3.4% |
8/238 |
External ear malformation |
2.5% |
6/238 |
Overfolded helix |
2.1% |
5/238 |
Preauricular pit |
2.1% |
5/238 |
Cupped ear |
1.7% |
4/238 |
Forward facing earlobe |
1.3% |
3/238 |
Small earlobe |
1.3% |
3/238 |
Underdeveloped superior crus of antihelix |
1.3% |
3/238 |
Abnormal location of ears |
0.8% |
2/238 |
Abnormality of earlobe |
0.8% |
2/238 |
Cholesteatoma |
0.8% |
2/238 |
Thickened helices |
0.8% |
2/238 |
Abnormality of periauricular region |
0.4% |
1/238 |
Absent earlobe |
0.4% |
1/238 |
Asymmetry of the ears |
0.4% |
1/238 |
Cleft helix |
0.4% |
1/238 |
Darwin tubercle of helix |
0.4% |
1/238 |
Large earlobe |
0.4% |
1/238 |
Long ear |
0.4% |
1/238 |
Long eyelashes |
0.4% |
1/238 |
Microtia |
0.4% |
1/238 |
Mild hearing impairment |
0.4% |
1/238 |
Periauricular skin pits |
0.4% |
1/238 |
Prominent ear helix |
0.4% |
1/238 |
Prominent crus of helix |
0.4% |
1/238 |
Recurrent infections of the middle ear |
0.4% |
1/238 |
Recurrent otitis media |
0.4% |
1/238 |
Satyr ear |
0.4% |
1/238 |
Thick eyebrow |
0.4% |
1/238 |
Underdeveloped nasal alae |
0.4% |
1/238 |
Abnormality of the eye |
86.5% |
212/245 |
Thick eyebrow |
56.3% |
138/245 |
Long eyelashes |
46.5% |
114/245 |
Downslanted palpebral fissures |
15.1% |
37/245 |
Synophrys |
7.8% |
19/245 |
Ptosis |
7.3% |
18/245 |
Periorbital wrinkles |
6.9% |
17/245 |
Epicanthus |
5.7% |
14/245 |
Hypertelorism |
5.7% |
14/245 |
Upslanted palpebral fissure |
5.7% |
14/245 |
Abnormality of the lacrimal duct |
4.1% |
10/245 |
Long palpebral fissure |
4.1% |
10/245 |
Bilateral ptosis |
3.3% |
8/245 |
Strabismus |
3.3% |
8/245 |
Prominent eyelashes |
2.9% |
7/245 |
Highly arched eyebrow |
2.4% |
6/245 |
Small palpebral fissure |
2.4% |
6/245 |
Unilateral ptosis |
2.4% |
6/245 |
Facial wrinkling |
2.0% |
5/245 |
Short palpebral fissure |
1.6% |
4/245 |
Proptosis |
1.2% |
3/245 |
Abnormality of the nasolacrimal system |
0.8% |
2/245 |
Abnormality of the eye |
0.8% |
2/245 |
Abnormality of the periorbital region |
0.8% |
2/245 |
Decreased lacrimation |
0.8% |
2/245 |
Esotropia |
0.8% |
2/245 |
Horizontal nystagmus |
0.8% |
2/245 |
Nasolacrimal duct obstruction |
0.8% |
2/245 |
Abnormality of the eyelashes |
0.4% |
1/245 |
Blue sclerae |
0.4% |
1/245 |
Broad forehead |
0.4% |
1/245 |
Congenital ptosis |
0.4% |
1/245 |
Deeply set eye |
0.4% |
1/245 |
Excessive wrinkled skin |
0.4% |
1/245 |
Exotropia |
0.4% |
1/245 |
High forehead |
0.4% |
1/245 |
Lacrimal duct stenosis |
0.4% |
1/245 |
Lisch nodules |
0.4% |
1/245 |
Long eyebrows |
0.4% |
1/245 |
Lower eyelid edema |
0.4% |
1/245 |
Medial flaring of the eyebrow |
0.4% |
1/245 |
Muscular hypotonia of the trunk |
0.4% |
1/245 |
Periorbital fullness |
0.4% |
1/245 |
Prominent epicanthal folds |
0.4% |
1/245 |
Redundant skin |
0.4% |
1/245 |
Short eyelashes |
0.4% |
1/245 |
Sparse eyebrow |
0.4% |
1/245 |
Telecanthus |
0.4% |
1/245 |
Unilateral narrow palpebral fissure |
0.4% |
1/245 |
Abnormality of the nose |
78.5% |
190/242 |
Broad nasal tip |
40.5% |
98/242 |
Thick nasal alae |
27.3% |
66/242 |
Wide nasal bridge |
23.1% |
56/242 |
Wide nasal base |
18.2% |
44/242 |
Anteverted nares |
17.4% |
42/242 |
Short nose |
12.4% |
30/242 |
Depressed nasal bridge |
11.6% |
28/242 |
Long nose |
7.9% |
19/242 |
Bulbous nose |
4.1% |
10/242 |
Wide nose |
4.1% |
10/242 |
Prominent nasal tip |
3.3% |
8/242 |
Prominent nasal bridge |
2.1% |
5/242 |
Abnormality of the columella |
1.7% |
4/242 |
Abnormality of the nose |
1.2% |
3/242 |
Long philtrum |
1.2% |
3/242 |
Narrow nasal tip |
1.2% |
3/242 |
Narrow nasal bridge |
0.8% |
2/242 |
Thick lower lip vermilion |
0.8% |
2/242 |
Abnormality of the nasal alae |
0.4% |
1/242 |
Abnormal nasal morphology |
0.4% |
1/242 |
Abnormality of the nasal bridge |
0.4% |
1/242 |
Abnormality of the nasal tip |
0.4% |
1/242 |
Broad philtrum |
0.4% |
1/242 |
Choanal atresia |
0.4% |
1/242 |
Flat nasal alae |
0.4% |
1/242 |
Hypodontia |
0.4% |
1/242 |
Low hanging columella |
0.4% |
1/242 |
Narrow nasal base |
0.4% |
1/242 |
Nasal obstruction |
0.4% |
1/242 |
Nasal polyposis |
0.4% |
1/242 |
Papule |
0.4% |
1/242 |
Prominent nose |
0.4% |
1/242 |
Retrognathia |
0.4% |
1/242 |
Short philtrum |
0.4% |
1/242 |
Thick upper lip vermilion |
0.4% |
1/242 |
Thick vermilion border |
0.4% |
1/242 |
Thin lower lip vermilion |
0.4% |
1/242 |
Thin upper lip vermilion |
0.4% |
1/242 |
Underdeveloped nasal alae |
0.4% |
1/242 |
Abnormality of the mouth |
92.7% |
229/247 |
Wide mouth |
50.6% |
125/247 |
Thick lower lip vermilion |
49.0% |
121/247 |
Thin upper lip vermilion |
27.9% |
69/247 |
Long philtrum |
23.1% |
57/247 |
Thick upper lip vermilion |
20.6% |
51/247 |
Everted lower lip vermilion |
20.2% |
50/247 |
Broad philtrum |
15.4% |
38/247 |
Short philtrum |
13.4% |
33/247 |
Widely spaced teeth |
13.0% |
32/247 |
Delayed eruption of primary teeth |
12.1% |
30/247 |
High palate |
11.7% |
29/247 |
Delayed eruption of permanent teeth |
7.7% |
19/247 |
Cleft palate |
4.9% |
12/247 |
Gingival overgrowth |
4.5% |
11/247 |
Macroglossia |
4.5% |
11/247 |
Micrognathia |
4.0% |
10/247 |
Hypodontia |
3.2% |
8/247 |
Bifid uvula |
2.0% |
5/247 |
Coarse facial features |
2.0% |
5/247 |
Open mouth |
2.0% |
5/247 |
Abnormality of the mouth |
1.6% |
4/247 |
Microdontia |
1.6% |
4/247 |
Retrognathia |
1.6% |
4/247 |
Abnormality of the philtrum |
1.2% |
3/247 |
Irregular dentition |
1.2% |
3/247 |
Narrow mouth |
1.2% |
3/247 |
Thin lower lip vermilion |
1.2% |
3/247 |
Abnormality of the teeth |
0.8% |
2/247 |
Abnormality of dental enamel |
0.8% |
2/247 |
Abnormality of the palate |
0.8% |
2/247 |
Ankyloglossia |
0.8% |
2/247 |
Carious teeth |
0.8% |
2/247 |
Dental malocclusion |
0.8% |
2/247 |
High, narrow palate |
0.8% |
2/247 |
Mandibular prognathia |
0.8% |
2/247 |
Misalignment of teeth |
0.8% |
2/247 |
Protruding tongue |
0.8% |
2/247 |
Abnormality of mouth size |
0.4% |
1/247 |
Abnormality of the tongue |
0.4% |
1/247 |
Abnormality of the gingiva |
0.4% |
1/247 |
Absent speech |
0.4% |
1/247 |
Advanced eruption of teeth |
0.4% |
1/247 |
Cleft soft palate |
0.4% |
1/247 |
Conical tooth |
0.4% |
1/247 |
Delayed eruption of teeth |
0.4% |
1/247 |
Downturned corners of mouth |
0.4% |
1/247 |
Everted upper lip vermilion |
0.4% |
1/247 |
Excessive salivation |
0.4% |
1/247 |
Growth delay |
0.4% |
1/247 |
Hypoplasia of the primary teeth |
0.4% |
1/247 |
Hypoplasia of teeth |
0.4% |
1/247 |
Overbite |
0.4% |
1/247 |
Pes planus |
0.4% |
1/247 |
Prominent palatine ridges |
0.4% |
1/247 |
Short chin |
0.4% |
1/247 |
Small, conical teeth |
0.4% |
1/247 |
Smooth philtrum |
0.4% |
1/247 |
Submucous cleft lip |
0.4% |
1/247 |
Submucous cleft soft palate |
0.4% |
1/247 |
Thick vermilion border |
0.4% |
1/247 |
Widely spaced primary teeth |
0.4% |
1/247 |
Widely-spaced incisors |
0.4% |
1/247 |
Visual and hearing impairments |
|
|
Abnormal hearing |
28.1% |
66/235 |
Hearing impairment |
11.9% |
28/235 |
Glue ear |
5.5% |
13/235 |
Conductive hearing impairment |
3.8% |
9/235 |
Bilateral conductive hearing impairment |
1.3% |
3/235 |
Bilateral sensorineural hearing impairment |
1.3% |
3/235 |
Moderate sensorineural hearing impairment |
1.3% |
3/235 |
Sensorineural hearing impairment |
1.3% |
3/235 |
Severe sensorineural hearing impairment |
1.3% |
3/235 |
Mild conductive hearing impairment |
0.9% |
2/235 |
Mild hearing impairment |
0.9% |
2/235 |
Abnormality of the tympanic membrane |
0.4% |
1/235 |
Abnormality of the middle ear |
0.4% |
1/235 |
Hearing abnormality |
0.4% |
1/235 |
Hyperacusis |
0.4% |
1/235 |
Mixed hearing impairment |
0.4% |
1/235 |
Moderate conductive hearing impairment |
0.4% |
1/235 |
Otitis media |
0.4% |
1/235 |
Progressive sensorineural hearing impairment |
0.4% |
1/235 |
Recurrent otitis media |
0.4% |
1/235 |
Severe hearing impairment |
0.4% |
1/235 |
Unilateral |
0.4% |
1/235 |
Abnormal vision |
54.5% |
120/220 |
Myopia |
21.4% |
47/220 |
Strabismus |
12.3% |
27/220 |
Hypermetropia |
7.7% |
17/220 |
Astigmatism |
7.3% |
16/220 |
Visual impairment |
6.8% |
15/220 |
Severe Myopia |
5.5% |
12/220 |
Nystagmus |
3.6% |
8/220 |
Abnormality of refraction |
3.2% |
7/220 |
Exotropia |
2.3% |
5/220 |
Unilateral strabismus |
1.4% |
3/220 |
Abnormality of vision |
0.9% |
2/220 |
Amblyopia |
0.9% |
2/220 |
Glaucoma |
0.9% |
2/220 |
Optic nerve hypoplasia |
0.9% |
2/220 |
Abnormality of the optic disc |
0.5% |
1/220 |
Blurred vision |
0.5% |
1/220 |
Cataract |
0.5% |
1/220 |
Coloboma |
0.5% |
1/220 |
Congenital cataract |
0.5% |
1/220 |
Corneal ulceration |
0.5% |
1/220 |
Cortical visual impairment |
0.5% |
1/220 |
Esotropia |
0.5% |
1/220 |
Increased intraocular pressure |
0.5% |
1/220 |
Keratoconus |
0.5% |
1/220 |
Lattice corneal dystrophy |
0.5% |
1/220 |
Optic nerve coloboma |
0.5% |
1/220 |
Peripapillary chorioretinal atrophy |
0.5% |
1/220 |
Heart |
|
|
Abnormality of the heart |
25.3% |
55/217 |
Atria septal defect |
8.3% |
18/217 |
Ventricular septal defect |
4.1% |
9/217 |
Patent foramen ovale |
3.2% |
7/217 |
Abnormality of the aortic valve |
1.4% |
3/217 |
Heart murmur |
1.4% |
3/217 |
Mitral regurgitation |
1.4% |
3/217 |
Abnormality of the atrial septum |
0.9% |
2/217 |
Abnormal heart morphology |
0.9% |
2/217 |
Abnormality of the aortic arch |
0.9% |
2/217 |
Bicuspid aortic valve |
0.9% |
2/217 |
Coarctation of aorta |
0.9% |
2/217 |
Patent ductus arteriosus |
0.9% |
2/217 |
Secundum atrial septal defect |
0.9% |
2/217 |
Abnormality of the vasculature |
0.5% |
1/217 |
Abnormality of the vena cava |
0.5% |
1/217 |
Abnormality of the left ventricle |
0.5% |
1/217 |
Abnormality of the cardiac septa |
0.5% |
1/217 |
Abnormality of the pulmonary artery |
0.5% |
1/217 |
Abnormality of the tricuspid valve |
0.5% |
1/217 |
Arrhythmia |
0.5% |
1/217 |
Atrioventricular block |
0.5% |
1/217 |
Atrioventricular canal defect |
0.5% |
1/217 |
Bradycardia |
0.5% |
1/217 |
Congestive heart failure |
0.5% |
1/217 |
Cyanosis |
0.5% |
1/217 |
Dilated cardiomyopathy |
0.5% |
1/217 |
Hypoplastic left heart |
0.5% |
1/217 |
Hypoxemia |
0.5% |
1/217 |
Impaired left ventricular function |
0.5% |
1/217 |
Left-to-right shunt |
0.5% |
1/217 |
Non-restrictive ventricular septal defect |
0.5% |
1/217 |
Primum atrial septal defect |
0.5% |
1/217 |
Pulmonic stenosis |
0.5% |
1/217 |
Right ventricular dilatation |
0.5% |
1/217 |
Supraventricular arrhythmia |
0.5% |
1/217 |
Ventricular extrasystoles |
0.5% |
1/217 |
Pulmonary |
|
|
Abnormality of the lungs |
26.2% |
11/42 |
Asthma |
7.1% |
3/42 |
Recurrent upper respiratory tract infections |
7.1% |
3/42 |
Chronic obstructive pulmonary disease |
2.4% |
1/42 |
Laryngomalacia |
2.4% |
1/42 |
Laryngotracheomalacia |
2.4% |
1/42 |
Neonatal respiratory distress |
2.4% |
1/42 |
Recurrent bronchitis |
2.4% |
1/42 |
Recurrent pneumonia |
2.4% |
1/42 |
Recurrent respiratory infections |
2.4% |
1/42 |
Recurrent lower respiratory tract infections |
2.4% |
1/42 |
Gastrointestinal |
|
|
Gastrointestinal abnormalities |
61.2% |
134/219 |
Constipation |
20.5% |
45/219 |
Feeding difficulties in infancy |
16.4% |
36/219 |
Gastroesophageal reflux |
11.4% |
25/219 |
Feeding difficulties |
10.5% |
23/219 |
Umbilical hernia |
4.1% |
9/219 |
Failure to thrive |
3.7% |
8/219 |
Diarrhea |
2.7% |
6/219 |
Dysphagia |
2.7% |
6/219 |
Nasogastric tube feeding in infancy |
2.7% |
6/219 |
Poor suck |
2.7% |
6/219 |
Inguinal hernia |
2.3% |
5/219 |
Failure to thrive in infancy |
1.8% |
4/219 |
Gastrostomy tube feeding in infancy |
1.8% |
4/219 |
Abnormality of the abdomen |
1.4% |
3/219 |
Pyloric stenosis |
1.4% |
3/219 |
Abnormality of the intestine |
0.9% |
2/219 |
Anal fistula |
0.9% |
2/219 |
Episodic vomiting |
0.9% |
2/219 |
Gastroparesis |
0.9% |
2/219 |
Hernia of the abdominal wall |
0.9% |
2/219 |
Intestinal malrotation |
0.9% |
2/219 |
Lactose intolerance |
0.9% |
2/219 |
Laryngomalacia |
0.9% |
2/219 |
Vomiting |
0.9% |
2/219 |
Abnormal vascular physiology |
0.5% |
1/219 |
Abnormality of the gastrointestinal tract |
0.5% |
1/219 |
Anteriorly placed anus |
0.5% |
1/219 |
Aspiration |
0.5% |
1/219 |
Celiac disease |
0.5% |
1/219 |
Chronic constipation |
0.5% |
1/219 |
Cow milk allergy |
0.5% |
1/219 |
Dehydration |
0.5% |
1/219 |
Esophagitis |
0.5% |
1/219 |
Gastrointestinal dysmotility |
0.5% |
1/219 |
Hepatosplenomegaly |
0.5% |
1/219 |
Hiatus hernia |
0.5% |
1/219 |
Hyperinsulinemia |
0.5% |
1/219 |
Intestinal obstruction |
0.5% |
1/219 |
Intestinal lymphangiectasia |
0.5% |
1/219 |
Malnutrition |
0.5% |
1/219 |
Ulcerative colitis |
0.5% |
1/219 |
Urogenital |
|
|
Abnormality of the urogenital system |
38.0% |
79/208 |
Bilateral cryptorchidism |
13.0% |
27/208 |
Cryptorchidism |
6.7% |
14/208 |
Unilateral cryptorchidism |
6.7% |
14/208 |
Hydronephrosis |
2.4% |
5/208 |
Nephrolithiasis |
2.4% |
5/208 |
Inguinal hernia |
1.9% |
4/208 |
Retractile testis |
1.9% |
4/208 |
Vesicoureteral reflux |
1.4% |
3/208 |
Abnormality of the urinary system |
1.0% |
2/208 |
Abnormality of the penis |
1.0% |
2/208 |
Abnormality of the genitourinary system |
1.0% |
2/208 |
Increased size of the clitoris |
1.0% |
2/208 |
Scrotal hypoplasia |
1.0% |
2/208 |
Abnormal renal morphology |
0.5% |
1/208 |
Abnormality of the urinary system physiology |
0.5% |
1/208 |
Abnormality of the testis |
0.5% |
1/208 |
Abnormality of the ureter |
0.5% |
1/208 |
Abnormality of the kidney |
0.5% |
1/208 |
Aplasia of the uterus |
0.5% |
1/208 |
Aplasia of the upper vagina |
0.5% |
1/208 |
Chronic kidney disease |
0.5% |
1/208 |
Clitoral hypertrophy |
0.5% |
1/208 |
Decreased testicular size |
0.5% |
1/208 |
Elevated serum creatinine |
0.5% |
1/208 |
Enuresis nocturna |
0.5% |
1/208 |
Functional abnormality of the bladder |
0.5% |
1/208 |
Hydrocele testis |
0.5% |
1/208 |
Hydroureter |
0.5% |
1/208 |
Hypoplastic male external genitalia |
0.5% |
1/208 |
Nephrotic syndrome |
0.5% |
1/208 |
Nephrocalcinosis |
0.5% |
1/208 |
Proteinuria |
0.5% |
1/208 |
Pyelonephritis |
0.5% |
1/208 |
Renal duplication |
0.5% |
1/208 |
Renal cyst |
0.5% |
1/208 |
Renal dysplasia |
0.5% |
1/208 |
Small scrotum |
0.5% |
1/208 |
Stage 5 chronic kidney disease |
0.5% |
1/208 |
Unilateral renal atrophy |
0.5% |
1/208 |
Ureteral duplication |
0.5% |
1/208 |
Urethral valve |
0.5% |
1/208 |
Urinary retention |
0.5% |
1/208 |
Webbed penis |
0.5% |
1/208 |
Skeleton |
|
|
Skeletal abnormalities |
88.4% |
213/241 |
Scoliosis |
19.9% |
48/241 |
Abnormality of the distal phalanx of the 5th finger |
16.2% |
39/241 |
Clinodactyly |
12.0% |
29/241 |
Prominent interphalangeal joints |
12.0% |
29/241 |
Short distal phalanx of finger |
11.6% |
28/241 |
Short 5th finger |
10.0% |
24/241 |
Sandal gap |
9.5% |
23/241 |
Delayed skeletal maturation |
8.3% |
20/241 |
Pes planus |
7.5% |
18/241 |
Short phalanx of finger |
7.5% |
18/241 |
Brachydactyly syndrome |
7.1% |
17/241 |
Joint laxity |
6.2% |
15/241 |
Long hallux |
5.8% |
14/241 |
Abnormality of the sternum |
5.4% |
13/241 |
Short stature |
5.4% |
13/241 |
Abnormality of the neck |
5.0% |
12/241 |
Brachycephaly |
3.3% |
8/241 |
Clinodactyly of the 5th finger |
3.3% |
8/241 |
Plagiocephaly |
3.3% |
8/241 |
Microcephaly |
2.9% |
7/241 |
Prominent fingertip pads |
2.9% |
7/241 |
Arthritis |
2.1% |
5/241 |
Dolichocephaly |
2.1% |
5/241 |
Frontal bossing |
2.1% |
5/241 |
Patellar dislocation |
2.1% |
5/241 |
Pectus excavatum |
2.1% |
5/241 |
All |
1.7% |
4/241 |
Broad thumb |
1.7% |
4/241 |
Hyperlordosis |
1.7% |
4/241 |
Short distal phalanx of the 5th finger |
1.7% |
4/241 |
Single transverse palmar crease |
1.7% |
4/241 |
Abnormality of the thumb |
1.2% |
3/241 |
Broad hallux |
1.2% |
3/241 |
Camptodactyly of finger |
1.2% |
3/241 |
Cone-shaped epiphysis |
1.2% |
3/241 |
Delayed eruption of permanent teeth |
1.2% |
3/241 |
Generalized hypotonia |
1.2% |
3/241 |
Hallux valgus |
1.2% |
3/241 |
Joint hypermobility |
1.2% |
3/241 |
Kyphosis |
1.2% |
3/241 |
Recurrent patellar dislocation |
1.2% |
3/241 |
Short distal phalanx of toe |
1.2% |
3/241 |
Short finger |
1.2% |
3/241 |
Abnormal joint morphology |
0.8% |
2/241 |
Abnormality of the distal phalanx of finger |
0.8% |
2/241 |
Accelerated skeletal maturation |
0.8% |
2/241 |
Aplasia/Hypoplasia of the phalanges of the hand |
0.8% |
2/241 |
Aplasia/Hypoplasia of the distal phalanges of the hand |
0.8% |
2/241 |
Broad hallux phalanx |
0.8% |
2/241 |
Broad phalanges of the hand |
0.8% |
2/241 |
Broad foot |
0.8% |
2/241 |
Broad phalanx of the toes |
0.8% |
2/241 |
Broad distal phalanx of finger |
0.8% |
2/241 |
Central hypotonia |
0.8% |
2/241 |
Curved phalanges of the 2nd finger |
0.8% |
2/241 |
Curved phalanges of the 5th finger |
0.8% |
2/241 |
Delayed eruption of primary teeth |
0.8% |
2/241 |
Genu valgum |
0.8% |
2/241 |
Short middle phalanx of the 5th finger |
0.8% |
2/241 |
Short metacarpal |
0.8% |
2/241 |
Short metatarsal |
0.8% |
2/241 |
Short foot |
0.8% |
2/241 |
Short toe |
0.8% |
2/241 |
Short neck |
0.8% |
2/241 |
Small hand |
0.8% |
2/241 |
Triphalangeal thumb |
0.8% |
2/241 |
Valgus foot deformity |
0.8% |
2/241 |
Widely spaced teeth |
0.8% |
2/241 |
Wide intermamillary distance |
0.8% |
2/241 |
Abnormality of the calvaria |
0.4% |
1/241 |
Abnormality of the scapula |
0.4% |
1/241 |
Abnormality of the tarsal bones |
0.4% |
1/241 |
Abnormality of the vertebrae |
0.4% |
1/241 |
Abnormality of the phalanges of the 5th finger |
0.4% |
1/241 |
Abnormal cervical curvature |
0.4% |
1/241 |
Abnormality of the hip bone |
0.4% |
1/241 |
Abnormality of the occipital bone |
0.4% |
1/241 |
Abnormal metacarpal morphology |
0.4% |
1/241 |
Adducted thumb |
0.4% |
1/241 |
Aplasia/Hypoplasia of the distal phalanges of the toes |
0.4% |
1/241 |
Aplasia/Hypoplasia of the 2nd finger |
0.4% |
1/241 |
Aplasia/Hypoplasia of fingers |
0.4% |
1/241 |
Aplasia/Hypoplasia of the distal phalanx of the 5th finger |
0.4% |
1/241 |
Aplasia/Hypoplasia of the nails |
0.4% |
1/241 |
Aplasia/Hypoplasia of the phalanges of the 5th toe |
0.4% |
1/241 |
Bilateral elbow dislocations |
0.4% |
1/241 |
Broad distal phalanges of all fingers |
0.4% |
1/241 |
Broad distal hallux |
0.4% |
1/241 |
Broad palm |
0.4% |
1/241 |
Camptodactyly |
0.4% |
1/241 |
Carious teeth |
0.4% |
1/241 |
Clinodactyly of the 4th finger |
0.4% |
1/241 |
Congenital hip dislocation |
0.4% |
1/241 |
Coronal craniosynostosis |
0.4% |
1/241 |
Curved hallux phalanx |
0.4% |
1/241 |
Curved thumb phalanx |
0.4% |
1/241 |
Curved phalanges of the 4th finger |
0.4% |
1/241 |
Deep plantar creases |
0.4% |
1/241 |
Delayed eruption of teeth |
0.4% |
1/241 |
Difficulty walking |
0.4% |
1/241 |
Dysharmonic delayed bone age |
0.4% |
1/241 |
Elbow dislocation |
0.4% |
1/241 |
Flat occiput |
0.4% |
1/241 |
Gingival overgrowth |
0.4% |
1/241 |
Hip dislocation |
0.4% |
1/241 |
Hypertrichosis |
0.4% |
1/241 |
Hypodontia |
0.4% |
1/241 |
Inguinal hernia |
0.4% |
1/241 |
Joint dislocation |
0.4% |
1/241 |
Kyphoscoliosis |
0.4% |
1/241 |
Lambdoidal craniosynostosis |
0.4% |
1/241 |
Limited elbow extension |
0.4% |
1/241 |
Long toe |
0.4% |
1/241 |
Long distal phalanx of finger |
0.4% |
1/241 |
Lower limb pain |
0.4% |
1/241 |
Macrocephaly at birth |
0.4% |
1/241 |
Macrocephaly |
0.4% |
1/241 |
Metatarsus adductus |
0.4% |
1/241 |
Micrognathia |
0.4% |
1/241 |
Mild short stature |
0.4% |
1/241 |
Oligodontia |
0.4% |
1/241 |
Overlapping toe |
0.4% |
1/241 |
Pes cavus |
0.4% |
1/241 |
Positional foot deformity |
0.4% |
1/241 |
Posterior plagiocephaly |
0.4% |
1/241 |
Proximal placement of thumb |
0.4% |
1/241 |
Rhizomelic arm shortening |
0.4% |
1/241 |
Rhizomelic leg shortening |
0.4% |
1/241 |
Rocker bottom foot |
0.4% |
1/241 |
Sacral dimple |
0.4% |
1/241 |
Short sternum |
0.4% |
1/241 |
Short phalanx of the 5th toe |
0.4% |
1/241 |
Shortening of all phalanges of fingers |
0.4% |
1/241 |
Shortening of all phalanges of the toes |
0.4% |
1/241 |
Short hallux |
0.4% |
1/241 |
Sparse scalp hair |
0.4% |
1/241 |
Spondylolysis |
0.4% |
1/241 |
Symphalangism affecting the phalanges of the 5th toe |
0.4% |
1/241 |
Talipes valgus |
0.4% |
1/241 |
Thick hair |
0.4% |
1/241 |
Thoracic scoliosis |
0.4% |
1/241 |
Toe syndactyly |
0.4% |
1/241 |
Toe walking |
0.4% |
1/241 |
Valgus hand deformity |
0.4% |
1/241 |
Skin / Hair / Nails |
|
|
Abnormality of the skin/hair/nails |
93.0% |
227/244 |
Hypertrichosis |
54.9% |
134/244 |
Sparse scalp hair |
35.2% |
86/244 |
Low anterior hairline |
27.0% |
66/244 |
Hypoplastic fifth fingernail |
20.1% |
49/244 |
Thick hair |
15.6% |
38/244 |
Prominent fingertip pads |
13.1% |
32/244 |
Low posterior hairline |
10.2% |
25/244 |
Eczema |
9.0% |
22/244 |
Generalized hypertrichosis |
8.2% |
20/244 |
Hypoplastic fifth toenail |
6.6% |
16/244 |
Small nail |
6.6% |
16/244 |
Hypoplastic toenails |
4.9% |
12/244 |
Hyperhidrosis |
4.5% |
11/244 |
Atopic dermatitis |
4.1% |
10/244 |
Fine hair |
4.1% |
10/244 |
Wide intermamillary distance |
4.1% |
10/244 |
Hypoplastic fingernail |
3.7% |
9/244 |
Nevus |
2.5% |
6/244 |
Single transverse palmar crease |
2.0% |
5/244 |
Abnormality of the nail |
1.6% |
4/244 |
Aplasia/Hypoplasia of the nails |
1.6% |
4/244 |
Excessive wrinkled skin |
1.6% |
4/244 |
Slow-growing nails |
1.6% |
4/244 |
Abnormality of the skin |
1.2% |
3/244 |
Abnormality of the scalp hair |
1.2% |
3/244 |
Coarse hair |
1.2% |
3/244 |
Cutis marmorata |
1.2% |
3/244 |
Hyperkeratosis |
1.2% |
3/244 |
Hyperpigmentation of the skin |
1.2% |
3/244 |
Sparse hair |
1.2% |
3/244 |
Thin fingernail |
1.2% |
3/244 |
Abnormally lax or hyperextensible skin |
0.8% |
2/244 |
Bilateral single transverse palmar creases |
0.8% |
2/244 |
Cafe-au-lait spot |
0.8% |
2/244 |
Hemangioma |
0.8% |
2/244 |
Hypopigmentation of the skin |
0.8% |
2/244 |
Jaundice |
0.8% |
2/244 |
Melanocytic nevus |
0.8% |
2/244 |
Numerous nevi |
0.8% |
2/244 |
Sacral dimple |
0.8% |
2/244 |
Short nail |
0.8% |
2/244 |
Short distal phalanx of finger |
0.8% |
2/244 |
Thickened skin |
0.8% |
2/244 |
Thin nail |
0.8% |
2/244 |
Thoracic hypertrichosis |
0.8% |
2/244 |
Abnormality of the palmar creases |
0.4% |
1/244 |
Abnormality of the hair |
0.4% |
1/244 |
Abnormality of the distal phalanx of the 5th finger |
0.4% |
1/244 |
Abnormality of hair growth rate |
0.4% |
1/244 |
Abnormal position of hair whorl |
0.4% |
1/244 |
Abnormality of hair growth |
0.4% |
1/244 |
Absent fifth toenail |
0.4% |
1/244 |
Absent fifth fingernail |
0.4% |
1/244 |
Acanthosis nigricans |
0.4% |
1/244 |
Alopecia of scalp |
0.4% |
1/244 |
Alopecia |
0.4% |
1/244 |
Aplastic/hypoplastic toenail |
0.4% |
1/244 |
Clinodactyly |
0.4% |
1/244 |
Clinodactyly of the 5th finger |
0.4% |
1/244 |
Clubbing |
0.4% |
1/244 |
Congenital, generalized hypertrichosis |
0.4% |
1/244 |
Congenital giant melanocytic nevus |
0.4% |
1/244 |
Curly hair |
0.4% |
1/244 |
Deep palmar crease |
0.4% |
1/244 |
Depigmentation/hyperpigmentation of skin |
0.4% |
1/244 |
Elbow hypertrichosis |
0.4% |
1/244 |
Facial hirsutism |
0.4% |
1/244 |
Facial hypertrichosis |
0.4% |
1/244 |
Few cafe-au-lait spots |
0.4% |
1/244 |
Frontal hirsutism |
0.4% |
1/244 |
High anterior hairline |
0.4% |
1/244 |
Hirsutism |
0.4% |
1/244 |
Hyperextensible skin |
0.4% |
1/244 |
Increased body weight |
0.4% |
1/244 |
Irregular hyperpigmentation |
0.4% |
1/244 |
Localized hirsutism |
0.4% |
1/244 |
Localized skin lesion |
0.4% |
1/244 |
Multiple cafe-au-lait spots |
0.4% |
1/244 |
Neoplasm of the skin |
0.4% |
1/244 |
Pallor |
0.4% |
1/244 |
Polyhydramnios |
0.4% |
1/244 |
Premature skin wrinkling |
0.4% |
1/244 |
Red hair |
0.4% |
1/244 |
Sacral hypertrichosis |
0.4% |
1/244 |
Short 5th finger |
0.4% |
1/244 |
Skin tags |
0.4% |
1/244 |
Slow-growing hair |
0.4% |
1/244 |
Slow-growing scalp hair |
0.4% |
1/244 |
Sparse eyebrow |
0.4% |
1/244 |
Spotty hyperpigmentation |
0.4% |
1/244 |
Striae distensae |
0.4% |
1/244 |
Thick eyebrow |
0.4% |
1/244 |
Thin toenail |
0.4% |
1/244 |
Urticaria |
0.4% |
1/244 |
Vitiligo |
0.4% |
1/244 |
Webbed neck |
0.4% |
1/244 |
Endocrine / Immunological / Metabolic |
|
|
Abnormality of the endocrine system |
18.4% |
34/185 |
Hypothyroidism |
7.0% |
13/185 |
Growth hormone deficiency |
5.4% |
10/185 |
Compensated hypothyroidism |
1.1% |
2/185 |
Diabetes mellitus |
1.1% |
2/185 |
Type II diabetes mellitus |
1.1% |
2/185 |
Abnormality of thyroid physiology |
0.5% |
1/185 |
Central hypothyroidism |
0.5% |
1/185 |
Congenital hypothyroidism |
0.5% |
1/185 |
Decreased circulating cortisol level |
0.5% |
1/185 |
Delayed puberty |
0.5% |
1/185 |
Elevated circulating parathyroid hormone (PTH) level |
0.5% |
1/185 |
Gynecomastia |
0.5% |
1/185 |
Increased circulating androgen level |
0.5% |
1/185 |
Increased serum free triiodothyronine (fT3) |
0.5% |
1/185 |
Precocious puberty |
0.5% |
1/185 |
Puberty and gonadal disorders |
0.5% |
1/185 |
Type I diabetes mellitus |
0.5% |
1/185 |
Abnormality of the metabolic system |
8.6% |
16/185 |
Hypercholesterolemia |
1.1% |
2/185 |
Hypocalcemia |
1.1% |
2/185 |
Abnormality of metabolism/homeostasis |
0.5% |
1/185 |
Anemia |
0.5% |
1/185 |
Diabetes mellitus |
0.5% |
1/185 |
Hypercalciuria |
0.5% |
1/185 |
Hyperglycemia |
0.5% |
1/185 |
Hyperammonemia |
0.5% |
1/185 |
Hypercalcemia |
0.5% |
1/185 |
Hyperinsulinemia |
0.5% |
1/185 |
Hypomagnesemia |
0.5% |
1/185 |
Methylmalonic acidemia |
0.5% |
1/185 |
Muscle abnormality related to mitochondrial dysfunction |
0.5% |
1/185 |
Neonatal hypoglycemia |
0.5% |
1/185 |
Obesity |
0.5% |
1/185 |
Type I diabetes mellitus |
0.5% |
1/185 |
Vitamin B12 deficiency |
0.5% |
1/185 |
Abnormality of the immune system |
33.2% |
70/211 |
Recurrent infections |
11.4% |
24/211 |
Recurrent upper respiratory tract infections |
7.1% |
15/211 |
Recurrent otitis media |
7.1% |
15/211 |
Eczema |
1.4% |
3/211 |
Recurrent lower respiratory tract infections |
1.4% |
3/211 |
Recurrent respiratory infections |
1.4% |
3/211 |
Recurrent urinary tract infections |
1.4% |
3/211 |
Respiratory infections in early life |
1.4% |
3/211 |
Abnormality of the immune system |
0.9% |
2/211 |
Allergy |
0.9% |
2/211 |
Asthma |
0.5% |
1/211 |
Bronchiolitis |
0.5% |
1/211 |
Conjunctivitis |
0.5% |
1/211 |
Decreased antibody level in blood |
0.5% |
1/211 |
Eosinophilia |
0.5% |
1/211 |
Lymphopenia |
0.5% |
1/211 |
Otitis media |
0.5% |
1/211 |
Panhypogammaglobulinemia |
0.5% |
1/211 |
Recurrent infections of the middle ear |
0.5% |
1/211 |
Recurrent bronchopulmonary infections |
0.5% |
1/211 |
Recurrent bronchitis |
0.5% |
1/211 |
Recurrent upper and lower respiratory tract infections |
0.5% |
1/211 |
Respiratory tract infection |
0.5% |
1/211 |
Seasonal allergy |
0.5% |
1/211 |
Small vessel vasculitis |
0.5% |
1/211 |
Neoplasia |
|
|
Neoplasia |
0.8% |
2/249 |
Brain neoplasm |
0.4% |
1/249 |
Leydig cell neoplasia |
0.4% |
1/249 |
Neoplasm |
0.4% |
1/249 |
Sertoli cell neoplasm |
0.4% |
1/249 |