Management

Currently, there are no clinical management guidelines for individuals with variants in the EHMT2 gene, as it is still a candidate gene for NDDs.

Management should be tailored to the individual clinical presentation. Recommended approaches may include:
●    Multidisciplinary follow-up (neurology, clinical genetics, physical therapy, speech and occupational therapy)
●    Developmental assessment and early intervention
●    Screening for comorbidities when clinically indicated
●    Individualized educational support

Additional diagnostic evaluations and therapeutic interventions should be guided by clinical findings. Long-term management requires ongoing clinical surveillance with periodic re-evaluations is recommended throughout childhood development.