Frequent features associated with LHX2 variants:
Developmental delay/ intellectual disability (14/16)
Behavioral abnormalities (including ASD) (10/12)
Speech impairment (10/11)
Microcephaly (7/10)
Facial dysmorphism (9/10)
Vision impairment (9/13)
MRI abnormalities (5/7)
Infrequent features associated with LHX2 variants:
Seizures (1/8)
Muscular hypotonia (3/9)
Feeding difficulties (2/8)
Cardiac defects (3/11)
Skeletal anomalies (3/11)
LHX2