RMND1 related disease is transmitted as autosomal recessive disorder, meaning that to be affected, an individual must inherit a mutation from the mother and one from the father. Mutations have been described along all the RMND1 gene. This gene produces a protein localized in the mitochondria, which are organelles responsible for the production of energy. Therefore, mutations in RMND1 cause alterations of mitochondria and energy defect.
RMND1