ADAT3

Clinical Characteristics

Mutations in the ADAT3 gene may cause the following signs and symptoms:

  • Intellectual disability
  • Strabismus (crossed eyes)
  • Microcephaly (smaller-than-normal head)
  • Hypotonia (reduced muscle tone) that can progress to spasticity
  • Abnormal brain findings on MRI imaging
  • Epilepsy
  • Unusual facial features
  • Hyperactive behaviour
  • Aggressive behaviour