There is no cure for SCA27B. The goals of treatment are to improve quality of life, maximize function, and reduce complications. This ideally involves multidisciplinary care and regular follow up by specialists in relevant fields, such as neurologists, ophthalmologists, physiotherapists, occupational therapists, speech and language therapists, and psychologists. A yearly follow up with a neurologist is recommended to monitor for new manifestations, disease progression, and address any new complications arising during disease evolution.
Adaptive devices, such as canes or walking sticks, may be used as needed to improve mobility. Self-directed exercise as prescribed by a physiotherapist may be beneficial.