LAMA5 disease is a hereditary pathology caused by a DNA mutation in the laminin alpha 5 chain protein. This disorder can be transmitted from one (dominant transmission) or both parents (recessive transmission). The laminin alpha 5 chain is a protein that interacts with several other proteins (for examples hormones and vitamins) and regulates their cellular distribution and function in all phases of human life. Its mutations cause defects in interaction with other molecules determining alterations in development and maintenance of all organs and tissues.
LAMA5