PRDM16

Management

The primary goal of LVNC management is to improve cardiac function and to prevent symptoms. In the presence of ventricular dysfunction, LVNC patients are at risk for thrombus formation within the trabeculated myocardial tissue. To reduce clot formation and the subsequent risk for stroke or other organ damage, oral anticoagulation may be recommended. Individuals with LVNC need to be followed by a cardiologist on a regular basis. Although critical for health, physical activity and exercise need to be carefully considered by the cardiologist according to the individual situation of the patient. In individuals with LVNC, which have a risk for sudden cardiac arrest, the use of an implantable cardioverter-defibrillator (ICD) may be recommended.

The primary goal of DCM management is to improve cardiac function and to prevent symptoms. Treatment may include medication with beta-blockers or ACE inhibitors. Other medications are applied to manage arrhythmias or other symptoms. Importantly, individuals with DCM need regular follow-up by an experienced cardiologist. The degree of physical activity and exercise needs to be determined on an individual basis. Individuals with DCM may have an increased risk for sudden cardiac arrest due to ventricular tachycardia. To reduce the risk of sudden cardiac arrest an implantable cardioverter-defibrillator (ICD) may be recommended.