Neurologic:
- Dandy-Walker malformation
- Cerebellar vermis hypoplasia
- Hypoplastic corpus callosum
- Brain atrophy
- Truncal hypotonia
- Peripheral hypertonia and hyperreflexia
Cardiovascular:
- Ventricular septal defect
- Valvular hypoplasia
Head and Neck:
- Various craniofacial malformations, including microphthalmia, hypertelorism, broad or depressed nasal bridge, cleft lip, and cleft palate
Skeletal:
- Hand and foot malformations, including syndactyly and camptodactyly