The clinical features of Alazami-Yuan syndrome include:
- Intellectual disability
- Delayed psychomotor development
- Poor speech
- Microcephaly
- Neonatal hypotonia
- Hyperactivity
- Variable dysmorphic features, including:
- Low frontal hairline
- Synophrys
- Prominent nose and nasal bridge
- Hypoplastic nasal wings
- Long columella
- Long philtrum
- Thin upper lip
- Microstomia
- High-arched palate
- Crowded teeth
- Long eyelashes
- Thick eyebrows
- Arched eyebrows
Other clinical features may include:
- Hyperactivity
- Hirsutism
- Cryptorchidism