Clinical features associated with the syndrome caused by mutations in the TGFB3 gene:
- Thoracic and abdominal aortic aneurysm and dissection
- Mitral valve prolapse or regurgitation
- Hypertelorism
- Exotropia
- Rethrognatia
- Bifid uvula or cleft palate
- Cervical spine instability
- Pectus excavatum/carinatum
- Scoliosis
- Club foot