This website provides information on patients with mutations in the AKT3 gene, including clinical data, molecular data, management and research options.

Disorders caused by mutations in the AKT3 gene include the following: The megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) syndrome, Focal brain malformations including hemimegalencephaly (HMEG) and focal cortical dysplasia (FCD), Diffuse megalencephaly (MEG) with polymicrogyria (similar to MCAP syndrome), Diffuse megalencephaly (MEG) without cortical dysplasia.

This website was created to share and collect information about clinic, management and research projects to gather more knowledge and provide better treatment of patients with mutations in the AKT3 gene.