DNMT3A

Management

We recommend a baseline echocardiogram and regular review for evolving scoliosis.

There may be a low risk of developing haematological malignancies. As there are currently no established surveillance programmes for haematological malignancies we recommend a low threshold for investigating any symptoms (such as easy bruising, persistent fatigue, recurrent infections and bleeding from gums/nose) that may be related to a haematological malignancy.