Skeletal
- Hyperextensibility of joints
- Dislocation of large joints
- Talipes equinovarus
- Scoliosis
- Kyphosis
- Lordosis
- Pectus carinatum
- Short stature
Eyes
- Severe myopia
- Glaucoma
- Retinal detachment
- Iris and chorioretinal coloboma
Hearing loss may also be present.