Currently, there is no known cure for an IQSEC2-related disorder. However, early intervention and educational programs can maximise learning and social development, and medications can help manage the symptoms.

Close monitoring by a paediatrician, comprehensive developmental assessment, audiometry and ophthalmology review are recommended for children with an IQSEC2-related disorder. Any concerns about possible seizures or mental health conditions should be promptly investigated by a neurologist or psychiatrist.