Without current curative treatment available, management is symptomatic.
Special attention should be given to:
- Growth and feeding: Nutritional support for feeding difficulties and management by a cleft/craniofacial team for those with palatal anomalies early in life
- Early referral for developmental support/special education
- Early recognition of behavioral problems and sleep disturbance
- Standard treatment for dental anomalies
- Low bone density with associated fractures can need medications such as bisphosphonates. Baseline bone density scan and vitamin D level measuring after 4 years of age is recommended
- Increased risk for seizure disorders. A baseline overnight electroencephalogram could be informative
- Baseline ophthalmology exam