TXNL4A

Management

The most important clinical intervention in a child with Burn McKeown syndrome is a newborn airway assessment for evidence of upper-airway obstruction with choanal stenosis/atresia. This will likely require surgical correction.
An audiology assessment is recommended to determine evidence of bilateral sensorineural hearing loss. An ophthalmology assessment for management/detection of lower-eyelid coloboma is indicated
Examination for midline cleft palate or unilateral cleft lip/palate with subsequent referral to a multidisciplinary cleft palate team. Cardiology assessment including cardiac imaging is indicated to establish evidence of congenital heart disease. Any cardiac disorder will require regular follow up.