This website provides information on patients with mutations in the PIGF gene, including clinical data, molecular data, management and research options.

The syndrome caused by mutations in the Phosphotidylinositol Glycan Anchor Biosynthesis Class F (PIGF) gene is called Onychodystrophy, osteodystrophy, impaired intellectual development, and seizures syndrome (OORS) and is a multisystem disorder that results in a similar phenotype to the DOORS syndrome. Not all individuals with a mutation in the PIGF gene have these features.

This website was created to share and collect information about clinic, management and research projects to gather more knowledge and provide better treatment of patients with mutations in the PIGF gene.

Philippe Campeau, MD, CHU Sainte-Justine Research Center, University of Montreal, Montreal, Canada, p.campeau@umontreal.ca

Coralie Michaud, MD, University of Montreal, Montreal, Canada, coralie.michaud@umontreal.ca

In collaboration with Drs Yoshiko Murakami, Taroh Kinoshita, Peter Krawitz and Allan Bayat.