This website provides information on patients with mutations in the TIAM1 gene, including clinical data, molecular data, management and research options.

The syndrome caused by mutations in the TIAM1 gene is a neurodevelopmental disorder with language delay and seizures (NEDLDS, OMIM#619908).
Not all individuals with a mutation in the TIAM1 gene have these features. The NEDLDS is caused by homozygous or compound heterozygous mutation in the TIAM1 gene.

This website was created to share and collect information about clinic, management and research projects to gather more knowledge and provide better treatment of patients with mutations in the TIAM1 gene.

Shenzhao Lu, PhD, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, US, shenzhao.lu@bcm.edu

Wendy K. Chung, MD, PhD, Departments of Pediatrics and Medicine, Columbia University, New York, US, wkc15@cumc.columbia.edu

Hugo J. Bellen, DVM, PhD, Departments of Molecular and Human Genetics and Neuroscience, Baylor College of Medicine, Houston, TX, US, hbellen@bcm.edu